Senior Scientist I/II- Cardiovascular Safety Pharmacologist

Profile

About AbbVie
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at ****target=_blank rel=no-follow>****Follow @abbvie on ****target=_blank rel=no-follow>Twitter, ****target=_blank rel=no-follow>Facebook, ****target=_blank rel=no-follow>Instagram, ****target=_blank rel=no-follow>YouTube and ****target=_blank rel=no-follow>LinkedIn.

Overview:

We are seeking a highly motivated senior scientist willing to learn/enhance current skills in large animal cardiovascular models.  The position is part of a key interface between internal stakeholders across AbbVie (i.e., Discovery, Development Sciences, Clinical Development, Preclinical Toxicology, and DMPK) as well as academic institutions and CRO’s specializing in cardiovascular safety pharmacology.  Using strong scientific and organizational skills, and knowledge of cardiovascular pharmacology, the successful candidate is expected to impact early decision-making for the AbbVie pharmaceutical pipeline.

Essential Job Function/Description:

• By leading and conducting in vivo cardiovascular studies, the successful candidate will contribute to the evaluation of safety pharmacology profiles on the cardiovascular system of evolving therapeutics during early drug discovery through early clinical drug development.
• Exhibit excellent interpersonal communication skills in a diverse cultural environment, working with talented safety pharmacology, discovery, and development teams to deliver results.
• Familiarity with basic cardiovascular physiology, data acquisition platforms, data analysis, strong computer and writing skills are essential.
• Conduct hypothesis-driven pre-clinical safety characterization focused on enabling accelerated decisions regarding target viability and internal prioritization of early lead molecules.
• Partner with key allied functions (e.g., DMPK, formulation scientists, anatomic and clinical pathologists, project leaders, discovery biologists, and synthetic chemists) for strategic design and implementation of experimental plans and protocols.
• Lead cross-functional efforts to investigate the mechanism of and the relevance of in vitro and in vivo data derived from state-of-the-art laboratories.
• Strategically apply expertise to elucidate mechanisms of toxicity, improve risk assessment, and solve scientific problems in a team setting with safety pharmacologists, regulatory and molecular toxicologists to guide advancement of Development compounds.
• Represent AbbVie in industrial consortia and professional organizations focused on improving non-clinical safety assessment.
• This position may recruit, train, and manage direct reports as appropriate.

Qualifications

Required:

• Bachelor’s Degree or equivalent education and typically 10-12 years of experience, Master’s Degree or equivalent education and typically 8-10 years of experience, PhD and typically 0-4 years of experience. Targeting degrees in Physiology, Pharmacology, or a related field
• Excellent oral and written communication skills
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Demonstrated ability to learn, understand and master new experimental techniques.
• Proven record of scientific contributions to the scientific community
• Ability to lead multidisciplinary scientific teams

Preferred:

• Experience within a Drug Discovery/Development environment is preferred.

• Experience with project management that provided decision-making outcomes is desired.

• At least 3-5 years of advanced technical knowledge of cardiovascular pharmacology in pharmaceutical research, academic or contract research environment is preferred. 

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
,identifier:{name:AbbVie,value:2204232,@type:PropertyValue},datePosted:2022-03-02T11:30:40 00:00,validThrough:2022-04-01T04:00:00 00:00,employmentType:FULL_TIME,hiringOrganization:{name:AbbVie,@id:397714,url:****County, Illinois,address:{addressCountry:US,addressLocality:Illinois,addressRegion:Illinois,postalCode:60086,@type:PostalAddress},@type:place},industry:Administration, Clinical, Science/R&D, Biotechnology,workHours:Full time,educationRequirements:Bachelors Degree,@type:JobPosting,@context:****

Company info

Sign Up Now - ProjectManagementCrossing.com